Dichloromethane (DCM)
CH₂Cl₂ · CAS 75-09-2
High-purity DCM across pharmaceutical, HPLC preparation, gradient, and anhydrous grades. The most widely used halogenated solvent for pharmaceutical extraction, preparative chromatography, and Fmoc/Boc solid-phase peptide synthesis.
Molecular Weight
84.93 g/mol
Boiling Point
39.6 °C
Density
1.325 g/mL
Molecular Formula
Available Grades
Analytical Specification
Analytical Specification Table
All values represent maximum allowable limits unless noted ≥. A lot-specific Certificate of Analysis (CoA) with ICP-MS, LPC, and GC data is issued for every shipment. Full data packages available on request.
| Parameter | Test Method | Unit | HPLC-G | HPLC | AR |
|---|---|---|---|---|---|
| Assay (GC) | GC-FID | % | ≥99.9 | ≥99.8 | ≥99.5 |
| Water Content (KF) | Karl Fischer | ppm | ≤20 | ≤30 | ≤200 |
| UV Absorbance 230 nm | UV-Vis | AU | ≤0.5 | ≤1.0 | — |
| UV Absorbance 254 nm | UV-Vis | AU | ≤0.01 | ≤0.02 | — |
| Acidity (as HCl) | Titration | ppm | ≤1 | ≤2 | ≤5 |
| Residue on Evaporation | Gravimetric | ppm | ≤1 | ≤2 | ≤5 |
★ G5 = SEMI C1 Tier D (6N grade). All metal values by ICP-MS. Particle counts by in-line LPC during ISO Class 3 fill. CoA available on request.
Grade Comparison
G1 → G5 Purity Scale
Select the grade that matches your process node and contamination budget. Every grade is available from PureTech with full lot CoA and ICP-MS data.
All grades tested by ICP-MS (28 elements), in-line LPC (ISO Class 3 fill), and Karl Fischer titration. G5 = SEMI C1 Tier D. Full CoA per lot. Request CoA template →
Application Areas
Where Dichloromethane Is Used
Semiconductor Process
- Organic polymer thin-film extraction
- photoresist strip research
Laboratory & Analytical
- Liquid-liquid extraction of organic compounds
- Preparative & column chromatography
- Solid-phase peptide synthesis (Fmoc/Boc SPPS)
- Soxhlet extraction of natural products
- NMR sample preparation
- GPC/SEC analysis
- Pharmaceutical API crystallization & purification
Industrial & Other
- Pharmaceutical API extraction & purification
- specialty coffee decaffeination
- industrial paint stripping
- polyurethane foam blowing
Packaging & Supply
Available Container Formats
Get Started
Request a Sample or
Technical Quote
Our application engineers respond with full CoA data, ICP-MS reports, and supply chain details within one business day.