High-purity options
Compare listed grades and current product-specific limits.
Superior ReagentPharmaceutical & GMP Solvents
Pharmaceutical DCM
CH₂Cl₂ · CAS 75-09-2
Pharmaceutical DCM considered for extraction, process work-up, API manufacturing. Selection begins with the application, critical limits, destination, pack and qualification plan.
A common starting point
extraction
Molecular weight
84.93 g/mol
Boiling point
39.6 °C
Density
1.325 g/mL
✓High-purity options✓Batch documentation✓Flexible packaging review
Product identity
- CAS number
- 75-09-2
- Formula
- CH₂Cl₂
- Boiling point
- 39.6 °C
- Density
- 1.325 g/mL
Product overview
A product route built around the application
Dichloromethane is considered for processes that need a consistent material, controlled critical impurities and a supply format that can move from qualification to routine use. The grade should be selected against the actual process—not a generic purity claim.
Controlled attributes
Focus testing on the impurities and performance risks that matter.
Supply planning
Align sample, production pack, forecast and document route early.
Application fit
Qualify Pharmaceutical DCM around the process
The product name begins the discussion. Critical attributes, test methods, packaging and routine supply conditions determine whether a candidate is useful.
extraction
Review the current specification and representative sample against the actual process and qualified baseline.
process work-up
Review the current specification and representative sample against the actual process and qualified baseline.
API manufacturing
Review the current specification and representative sample against the actual process and qualified baseline.
Before you specify
A better enquiry starts with four answers
A higher grade is not automatically the better choice. The useful option fits the process, analytical method, packaging route and qualification plan without adding controls the application does not need.
01
What role does the material perform in the process?
02
Which limits and methods control customer acceptance?
03
What sample and production pack represent routine use?
04
Which destination, documents, annual demand and timing apply?
Specification data
Compare the listed grade columns
This table is an indicative product overview for initial screening. Confirm the current controlled specification, test methods, reporting limits and available lot documentation before qualification or purchase.
| Parameter | Test method | Unit | HPLC gradient | HPLC | AR |
|---|---|---|---|---|---|
| Assay (GC) | GC-FID | % | ≥99.9 | ≥99.8 | ≥99.5 |
| Water Content (KF) | Karl Fischer | ppm | ≤20 | ≤30 | ≤200 |
| UV Absorbance 230 nm | UV-Vis | AU | ≤0.5 | ≤1.0 | — |
| UV Absorbance 254 nm | UV-Vis | AU | ≤0.01 | ≤0.02 | — |
| Acidity (as HCl) | Titration | ppm | ≤1 | ≤2 | ≤5 |
| Residue on Evaporation | Gravimetric | ppm | ≤1 | ≤2 | ≤5 |
Website values do not replace a signed sales specification. The agreed specification and lot-specific Certificate of Analysis govern supplied material.
Where this product is used
Application routes for Dichloromethane
These examples help with discovery. They are not claims of universal suitability; material compatibility, process performance and the controlled specification still need review.
Semiconductor & electronics
- Organic polymer thin-film extraction
- photoresist strip research
Laboratory & analytical
- Liquid-liquid extraction of organic compounds
- Preparative & column chromatography
- Solid-phase peptide synthesis (Fmoc/Boc SPPS)
- Soxhlet extraction of natural products
- NMR sample preparation
- GPC/SEC analysis
- Pharmaceutical API crystallization & purification
Industrial & other
- Pharmaceutical API extraction & purification
- specialty coffee decaffeination
- industrial paint stripping
- polyurethane foam blowing
Representative application cases
A practical evidence route for Dichloromethane
These are illustrative composite qualification scenarios, not named customer claims. Exact methods, limits and acceptance decisions belong to the customer’s controlled process.
Method-blank investigation
An analytical laboratory checks whether Dichloromethane (DCM) contributes to variability near its working reporting range.
Evidence route
The candidate lot is run through the laboratory’s actual preparation method; supplier data supports but does not replace local blank trending.
Multi-site reagent alignment
European and US laboratories compare Dichloromethane (DCM) for a shared analytical workflow.
Evidence route
Pack, sampling, storage, element panel and acceptance checks are aligned, followed by verification at each site.
Manufacturing advantage
A controlled route from purification to final filling
The supply route for Dichloromethane connects incoming-material review, product-specific treatment, controlled transfer, testing, filling and lot documentation. Exact equipment and controls depend on the qualified product and grade.
Purification
Product-specific separation or treatment route.
Filtration
Compatible filtration and controlled transfer.
Testing
Release against the agreed specification.
Clean filling
Pack, closure and lot identification review.
Quality assurance & documentation
Evidence your quality team can review
Documents are matched to the supplied product, grade, lot and destination. The links below request the current controlled version; they are not static files with uncertain revision status.
Certificate of Analysis
Lot-specific result or conformance format.
Request current file →Safety Data Sheet
Product- and market-specific hazard communication.
Request current file →Batch traceability
Connection between production, testing, pack and lot.
Request current file →Specification sheet
Agreed limits, units and referenced methods.
Request current file →Packaging options
Choose the pack with the handling route in mind
Availability varies by grade and destination. Confirm container material, closure, headspace, connection, minimum order, dangerous-goods route and qualification-lot needs.
Qualification & laboratory packs
For evaluation, method work and lower-volume routine use.
500 mL2.5 L5 L25 L
Drums & production packs
For regular production consumption and controlled dispensing.
25 L200 L
IBC & bulk routes
For higher-volume programmes after site, grade and logistics review.
Confirm by grade
Technical resources
Continue the technical review
Use application notes for context, then confirm current product documents before qualification.
Start a product review
Need a reliable supply route for Dichloromethane?
Send the application, current specification, critical limits, pack, destination and forecast so the response can be technically useful.