Chloroform (Trichloromethane)
CHCl₃ · CAS 67-66-3
High-purity chloroform for GPC/SEC polymer molecular weight analysis, NMR spectroscopy, pharmaceutical extraction, and DNA extraction. Stabilized with ethanol to prevent phosgene formation.
Molecular Weight
119.38 g/mol
Boiling Point
61.2 °C
Density
1.483 g/mL
Molecular Formula
Available Grades
Analytical Specification
Analytical Specification Table
All values represent maximum allowable limits unless noted ≥. A lot-specific Certificate of Analysis (CoA) with ICP-MS, LPC, and GC data is issued for every shipment. Full data packages available on request.
| Parameter | Test Method | Unit | HPLC-G | HPLC | AR |
|---|---|---|---|---|---|
| Assay (GC) | GC-FID | % | ≥99.9 | ≥99.8 | ≥99.0 |
| Water Content (KF) | Karl Fischer | ppm | ≤20 | ≤30 | ≤200 |
| Ethanol (stabilizer) | GC-FID | % | 0.5–1 | 0.5–1 | ≤1 |
| UV Absorbance 254 nm | UV-Vis | AU | ≤0.01 | ≤0.02 | — |
| Residue on Evaporation | Gravimetric | ppm | ≤1 | ≤2 | ≤5 |
★ G5 = SEMI C1 Tier D (6N grade). All metal values by ICP-MS. Particle counts by in-line LPC during ISO Class 3 fill. CoA available on request.
Grade Comparison
G1 → G5 Purity Scale
Select the grade that matches your process node and contamination budget. Every grade is available from PureTech with full lot CoA and ICP-MS data.
All grades tested by ICP-MS (28 elements), in-line LPC (ISO Class 3 fill), and Karl Fischer titration. G5 = SEMI C1 Tier D. Full CoA per lot. Request CoA template →
Application Areas
Where Chloroform Is Used
Semiconductor Process
- Organic semiconductor polymer characterization
- OTFT device organic layer research
Laboratory & Analytical
- GPC / SEC polymer MW determination
- NMR spectroscopy
- Pharmaceutical API extraction
- DNA/RNA extraction (phenol-chloroform method)
- Lipid class analysis (Folch method)
Industrial & Other
- Pharmaceutical API synthesis
- HCFC-22 refrigerant precursor
- polyurethane research
Packaging & Supply
Available Container Formats
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